Real-time Nanoparticle Size Characterization.
Under Real Process Conditions.
- Measure in real time, inline, or in closed containers
- Minimize sample handling and process disruption
- Support development, process optimization, and manufacturing
Better particle size insight for real processes.
Traditional particle sizing methods are often too slow, too labour-intensive, or too far removed from the actual process.
Typical challenges in nanoparticle size analysis
Concentrated samples are difficult to analyze
Many methods require dilution or struggle under process-relevant conditions.
Sampling may not reflect the real process
Removing samples from the process can introduce variation and limit real process insight.
Process visibility is limited
Without direct particle size insight, process changes are harder to detect and interpret.
Offline measurements slow down decisions
Sample preparation can delay screening, optimization, and process decisions.
How we address these challenges
InProcess-LSP enables particle size analysis under process-relevant conditions, helping teams reduce manual sampling, avoid unnecessary dilution, and gain faster feedback during development and manufacturing.
- Measure under process-relevant conditions
- Reduce sampling and sample handling
- Access particle size insight in seconds
Choose your system
The NanoFlowSizer
For real-time, inline nanoparticle size monitoring during process development and manufacturing.
The NanoLabSizer
For non-destructive nanoparticle size analysis in vials and other closed sample containers.
Choose your process stage
Different stages require different types of insight.
Explore how our technology supports each process stage, from early development to manufacturing.
- Compare formulations faster and study particle formation
- Real-time insights into nanoparticle behavior
- Understand the effect of process parameters
- Optimize with more confidence and less trial-and-error
- Ensure batch-to-batch consistency with inline production data.
- Support GMP-aligned manufacturing workflows
Choose your application area
LNPs
Support formulation, process optimization, and manufacturing of lipid nanoparticles with better particle size insight.
Transfection
Follow complex formation and better understand how formulation conditions affect nanoparticle size.
Biologics
Detect particle size changes and aggregation during development of sensitive biological formulations.
Nano-emulsions
Monitor droplet size during formulation and processing to improve product and process understanding.
This small instrument made a huge impact!
What differentiates our technology
Spatially Resolved DLS
Our patented technology is designed to deliver meaningful particle size insight under conditions where traditional methods often struggle.- High Turbidity Capability: Measure concentrated samples as they areβno dilution required
- Non-Invasive & Sterile: Keep your process closed and your samples uncontaminated
- Real-Time Feedback: results in seconds
- Flexible Integration: suitable for in-flow, at-line, online, and offline setups
Customer case studies
Explore how leading teams use the NanoFlowSizer to gain real-time nanoparticle process insight in development and manufacturing environments.
Reduce manual sampling, shorten development cycles, and improve process efficiency.
Technical Articles
- How do results from different dynamic light scattering instruments compare?
- How can you improve your PEI-based transient transfection process?
- Monitoring Protein Aggregation During Downstream Processing β Insights Using the NanoFlowSizer
- Lipid-Based Nanoparticles: Manufacturing and inline size Characterization